CONCOR AM 5mg/10mg 30tab

 CONCOR AM 5 mg / 10 mg Tablets (30 tablets) Active Ingredients: Bisoprolol Fumarate 5 mg – Beta-1 Selective Adrenergic Receptor Blocker (Beta-blocker) Amlodipine Besylate 10 mg – Calcium Channel Blocker (Dihydropyridine class) Therapeutic Class: Antihypertensive combination Dosage Form: Oral tablet Indications:CONCOR AM is indicated for the treatment of: Essential hypertension in patients whose blood pressure is not adequately controlled by monotherapy Chronic stable angina in patients requiring both beta-blocker and calcium channel blocker therapy Helps reduce cardiovascular risk in patients with both high blood pressure and angina Mechanism of Action: Bisoprolol reduces heart rate, myocardial oxygen demand, and cardiac output by selectively blocking β1-adrenergic receptors in the heart. Amlodipine inhibits calcium influx in vascular smooth muscle, causing vasodilation, lowering peripheral resistance and blood pressure, and improving blood flow in angina. Dosage and Administration: One tablet once daily, preferably at the same time each day Can be taken with or without food Dose adjustments should be based on the individual clinical response Not recommended as initial therapy Warnings and Precautions: Use with caution in patients with heart failure, bradycardia, asthma, or severe hepatic impairment Avoid abrupt withdrawal of bisoprolol – taper gradually Not recommended during pregnancy or breastfeeding without physician supervision Monitor heart rate, blood pressure, and signs of peripheral edema Side Effects:Common: bradycardia, dizziness, fatigue, peripheral edema, headache, hypotension Less common: nausea, cold extremities, sleep disturbances, palpitations, shortness of breathStorage: Store below 30°C, in a dry place, protected from light. Keep out of reach of children.