INEGY 10MG/40MG 28S

INEGY 10 mg / 40 mg Tablets (28 tablets)Active Ingredients: Ezetimibe 10 mg Simvastatin 40 mg Therapeutic Class: Lipid-Lowering Agent – Combination of Cholesterol Absorption Inhibitor and HMG-CoA Reductase Inhibitor (Statin)Indications: INEGY is indicated for: The treatment of primary hypercholesterolemia (heterozygous familial and non-familial) and mixed hyperlipidemia Homozygous familial hypercholesterolemia (HoFH), in combination with other lipid-lowering treatments Patients not adequately controlled with statin therapy alone It reduces total cholesterol, LDL-C, ApoB, and triglycerides while increasing HDL-C. Mechanism of Action: Ezetimibe inhibits the absorption of cholesterol in the small intestine, while Simvastatin inhibits cholesterol synthesis in the liver. Their complementary mechanisms provide a synergistic lipid-lowering effect.Dosage and Administration: One tablet once daily, in the evening, with or without food. Patients should follow a cholesterol-lowering diet. Dose adjustment may be needed in patients with renal impairment or when used with interacting medications.Warnings and Precautions: Contraindicated in active liver disease or persistent elevations in liver enzymes Avoid use during pregnancy and breastfeeding Monitor liver function and creatine kinase (CK) if muscle symptoms occur Side Effects: Common side effects include headache, abdominal pain, myalgia, fatigue, and elevated liver enzymes. Rare but serious effects include rhabdomyolysis and liver injury. Storage: Store below 30°C. Protect from light and moisture. Keep out of reach of children.